Molecular dynamics simulation of wild and mutant proteasome subunit beta type 8 (PSMB8) protein: Implications for restoration of inflammation in experimental autoimmune encephalomyelitis pathogenesis

Multiple Sclerosis (MS) is an autoimmune and chronic disease in the brain and spinal cord. MS has inflammatory progression characterized by its hallmark inflammatory plaques. The histological and clinical characteristics of MS are shared by Experimental Autoimmune Encephalomyelitis (EAE). Genetic an...

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Autori principali:	Shamrat Kumar Paul, Md Saddam, Nisat Tabassum, Mahbub Hasan
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	Elsevier 2025-01-01
Serie:	Heliyon
Soggetti:	Experimental autoimmune encephalomyelitis PSMB8 Molecular dynamics simulation GROMACS essential dynamic analysis
Accesso online:	http://www.sciencedirect.com/science/article/pii/S2405844024171976
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