Faecalibacterium prausnitzii, depleted in the Parkinson’s disease microbiome, improves motor deficits in α-synuclein overexpressing mice

Abstract Gut microbiome composition is altered in Parkinson’s disease (PD), the fastest-growing neurological condition, that is characterized by neurodegeneration, motor dysfunction, and is frequently accompanied by gastrointestinal (GI) symptoms. Notably, microbial taxa with anti-inflammatory prope...

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Hauptverfasser:	Anastasiya Moiseyenko, Giacomo Antonello, Aubrey M. Schonhoff, Joseph C. Boktor, Kaelyn Long, Blake Dirks, Anastasiya D. Oguienko, Alexander Viloria Winnett, Patrick Simpson, Dorsa Daeizadeh, Rustem F. Ismagilov, Rosa Krajmalnik-Brown, Nicola Segata, Levi D. Waldron, Sarkis K. Mazmanian
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	Nature Portfolio 2026-03-01
Schriftenreihe:	npj Parkinson's Disease
Online-Zugang:	https://doi.org/10.1038/s41531-026-01287-x
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