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Bilirubin metabolism in the liver orchestrates antiviral innate immunity in the body

Summary: Bilirubin metabolism crucially maintains normal liver function, but whether it contributes to antiviral immunity remains unknown. Here, we reveal that the liver bilirubin metabolic pathway facilitates antiviral innate immunity of the body. We discovered that viral infection upregulates urid...

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Principais autores: Qian Du, Wei He, Xiangjie Chen, Jin Liu, Mingcheng Guan, Yichang Chen, Meixia Chen, Yukang Yuan, Yibo Zuo, Ying Miao, Qin Wang, Haiyan Zhou, Yanli Liu, Jingting Jiang, Hui Zheng
Format: Artigo
Sprog:Inglês
Udgivet: Elsevier 2025-04-01
Serier:Cell Reports
Fag:
CP: Metabolism
CP: Immunology
Online adgang:http://www.sciencedirect.com/science/article/pii/S2211124725002529
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