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Arisaema Cum Bile possesses significantly antiepileptic effects through regulation of PI3K/Akt/Nrf2 signaling pathways

This paper intended to study the mechanism and active ingredients of ACB anti-epilepsy. The antiepileptic activity of ACB validated in PTZ kindled rats, ACB could increase the seizure latency and reduce seizure duration, attenuate spatial learning and memory deficits, improve hippocampus neuronal da...

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Principais autores: Lian Zhong, Chengxun He, Meiyan Li, Xu Wu, Yan Gou, Zhao Geng, Chengjun He, Chongbo Zhao, Chunjie Wu
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis Group 2024-12-01
coleção:Journal of Taibah University for Science
Assuntos:
Arisaema Cum Bile (ACB)
epilepsy
network pharmacology
PI3K/Akt/Nrf2 signaling pathway
apoptosis
Acesso em linha:https://www.tandfonline.com/doi/10.1080/16583655.2023.2289239
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