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Increased nociceptive behaviors and spinal c-Fos expression in the formalin test in a rat repeated cold stress model

Repeated cold stress (RCS) can trigger the development of fibromyalgia (FM)-like symptoms, including persistent deep-tissue pain, although nociceptive changes to the skin have not been fully characterized. Using a rat RCS model, we investigated nociceptive behaviors induced by noxious mechanical, th...

Ausführliche Beschreibung

Gespeichert in:
Hauptverfasser: Teruaki Nasu, Riku Kainuma, Hiroki Ota, Kazue Mizumura, Toru Taguchi
Format: Artigo
Sprache:Inglês
Veröffentlicht: Elsevier 2024-01-01
Schriftenreihe:Neuroscience Research
Schlagworte:
Repeated cold stress
Stress-induced pain
Fibromyalgia
Von Frey test
Hargreaves’ test
Formalin test
Online-Zugang:http://www.sciencedirect.com/science/article/pii/S0168010223001347
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