A specific inhibitor of protein kinase CK2 delays gamma-H2Ax foci removal and reduces clonogenic survival of irradiated mammalian cells
<p>Abstract</p> <p>Background</p> <p>The protein kinase CK2 sustains multiple pro-survival functions in cellular DNA damage response and its level is tightly regulated in normal cells but elevated in cancers. Because CK2 is thus considered as potential therapeutic target, DNA double-strand break (DS...
Gespeichert in:
| Hauptverfasser: | , , , , |
|---|---|
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
BMC
2011-02-01
|
| Schriftenreihe: | Radiation Oncology |
| Online-Zugang: | http://www.ro-journal.com/content/6/1/15 |
| Tags: |
Keine Tags, Fügen Sie das erste Tag hinzu!
|