Regulation of Human Endogenous Metabolites by Drug Transporters and Drug Metabolizing Enzymes: An Analysis of Targeted SNP-Metabolite Associations

Drug transporters and drug-metabolizing enzymes are primarily known for their role in the absorption, distribution, metabolism, and excretion (ADME) of small molecule drugs, but they also play a key role in handling endogenous metabolites. Recent cross-tissue co-expression network analyses have reve...

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Autori principali:	Jeffry C. Granados, Jeramie D. Watrous, Tao Long, Sara Brin Rosenthal, Susan Cheng, Mohit Jain, Sanjay K. Nigam
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	MDPI AG 2023-01-01
Serie:	Metabolites
Soggetti:	transporters enzymes ADME metabolomics SNPs pharmacogenomics
Accesso online:	https://www.mdpi.com/2218-1989/13/2/171
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