Chromobox 3 assembles an epigenetic complex contributing to cystathionine γ-lyase–mediated protection against aortic aneurysm/dissection

Abstract Hydrogen sulfide (H₂S), generated by cystathionine γ-lyase (CSE), protects against aortic aneurysm and dissection (AAD), yet its role in extracellular matrix (ECM) regulation remains unclear. Here, we demonstrate that CSE expression is markedly attenuated in vascular smooth muscle cells (VS...

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Detalhes bibliográficos

Principais autores:	Ying Zhao, Changting Cui, Huimin Gao, Yan Yao, Yaping Niu, Ling Cheng, Xiaodie Shao, Haizeng Zhang, Yuan Wang, Yuanzhen Lin, Zengxiang Dong, He Wu, Zhenzhen Chen, Liming Yang, Bin Geng
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Nature Portfolio 2026-06-01
coleção:	Nature Communications
Acesso em linha:	https://doi.org/10.1038/s41467-026-74048-2
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