Computational Modeling of Substrate-Dependent Mitochondrial Respiration and Bioenergetics in the Heart and Kidney Cortex and Outer Medulla

Abstract Integrated computational modeling provides a mechanistic and quantitative framework to characterize alterations in mitochondrial respiration and bioenergetics in response to different metabolic substrates in-silico. These alterations play critical roles in the pathogenesis of diseases affec...

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Principais autores:	Shima Sadri, Xiao Zhang, Said H Audi, Allen W Cowley , Ranjan K Dash
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Physiological Society 2023-01-01
coleção:	Function
Assuntos:	mitochondrial metabolism forward and reverse electron transfer respiration and bioenergetics oxidative phosphorylation substrate utilization computational modeling
Acesso em linha:	https://journals.physiology.org/doi/10.1093/function/zqad038
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