Targeting the Hsp90-Cdc37-client protein interaction to disrupt Hsp90 chaperone machinery
Abstract Heat shock protein 90 (Hsp90) is a critical molecular chaperone protein that regulates the folding, maturation, and stability of a wide variety of proteins. In recent years, the development of Hsp90-directed inhibitors has grown rapidly, and many of these inhibitors have entered clinical tr...
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| 主要な著者: | , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
BMC
2018-04-01
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| シリーズ: | Journal of Hematology & Oncology |
| 主題: | |
| オンライン･アクセス: | http://link.springer.com/article/10.1186/s13045-018-0602-8 |
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