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Telomeric double-strand DNA-binding proteins DTN-1 and DTN-2 ensure germline immortality in Caenorhabditis elegans

Telomeres are nucleoprotein complexes at the ends of chromosomes and are indispensable for the protection and lengthening of terminal DNA. Despite the evolutionarily conserved roles of telomeres, the telomeric double-strand DNA (dsDNA)-binding proteins have evolved rapidly. Here, we identified doubl...

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Principais autores: Io Yamamoto, Kexin Zhang, Jingjing Zhang, Egor Vorontsov, Hiroki Shibuya
Format: Artigo
Sprog:Inglês
Udgivet: eLife Sciences Publications Ltd 2021-01-01
Serier:eLife
Fag:
telomere
shelterin
POT-1
POT-2
DTN-1
DTN-2
Online adgang:https://elifesciences.org/articles/64104
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