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Cultured brain pericytes adopt an immature phenotype and require endothelial cells for expression of canonical markers and ECM genes

Pericytes (PCs) are essential components of the blood brain barrier. Brain PCs are critical for dynamically regulating blood flow, for maintaining vascular integrity and their dysregulation is associated with a myriad of disorders such as Alzheimer’s disease. To understand their physiological and mo...

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Bibliographic Details
Main Authors: Fabiana Oliveira, Olga Bondareva, Jesús Rafael Rodríguez-Aguilera, Bilal N. Sheikh
Format: Artigo
Language:Inglês
Published: Frontiers Media S.A. 2023-05-01
Series:Frontiers in Cellular Neuroscience
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fncel.2023.1165887/full
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