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3plex enables deep computational investigation of triplex forming lncRNAs

Long non-coding RNAs (lncRNAs) regulate gene expression through different molecular mechanisms, including DNA binding via the formation of RNA:DNA:DNA triple helices (TPXs). Despite the increasing amount of experimental evidence, TPXs investigation remains challenging. Here we present 3plex, a softw...

Ausführliche Beschreibung

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Bibliografische Detailangaben
Hauptverfasser: Chiara Cicconetti, Andrea Lauria, Valentina Proserpio, Marco Masera, Annalaura Tamburrini, Mara Maldotti, Salvatore Oliviero, Ivan Molineris
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Association for the Advancement of Science (AAAS) 2023-01-01
Schriftenreihe:Computational and Structural Biotechnology Journal
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Online-Zugang:http://www.sciencedirect.com/science/article/pii/S2001037023001988
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