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Fingolimod as a potent anti-Staphylococcus aureus: pH-dependent cell envelope damage and eradication of biofilms/persisters

Abstract Background The urgent need for new antibacterial drugs has driven interest in repurposing therapies to combat Gram-positive biofilms and persisters. Fingolimod, an Food and Drug Administration (FDA)-approved drug for multiple sclerosis, shows bactericidal activity, particularly against Meth...

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Auteurs principaux: Yongpeng Shang, Yu Huang, Qingyin Meng, Zhijian Yu, Zewen Wen, Fangyou Yu
Format: Artigo
Langue:Inglês
Publié: BMC 2025-05-01
Collection:BMC Microbiology
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Accès en ligne:https://doi.org/10.1186/s12866-025-03973-x
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