Landscape of gene fusions in hormone receptor-positive breast cancer reveals ADK fusions as drivers of progression and potential therapeutic targets

Abstract Gene fusions are becoming critical oncogenic drivers with potential therapeutic relevance across various cancers. However, their roles and clinical implications in breast cancer remain largely unexplored. In this study, we leveraged a large-scale multiomics cohort and a drug screening platf...

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Hauptverfasser:	Yang Ou-Yang, Ding Ma, Cai-Jin Lin, Yun-Song Yang, Cheng-Lin Liu, Jing Hou, Xi Jin, Zhi-Ming Shao, Yi-Zhou Jiang
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	Nature Publishing Group 2025-11-01
Schriftenreihe:	Cell Discovery
Online-Zugang:	https://doi.org/10.1038/s41421-025-00830-z
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