Difference in Mono-O-Glucosylation of Ras Subtype GTPases Between Toxin A and Toxin B From Clostridioides difficile Strain 10463 and Lethal Toxin From Clostridium sordellii Strain 6018

Clostridioides difficile toxin A (TcdA) and Toxin B (TcdB) trigger inflammasome activation with caspase-1 activation in cultured cells, which in turn induce the release of IL-6, IFN-γ, and IL-8. Release of these proinflammatory responses is positively regulated by Ras-GTPases, which leads to the hyp...

Täydet tiedot

Bibliografiset tiedot

Päätekijät:	Harald Genth, Johannes Junemann, Chantal M. Lämmerhirt, Arlen-Celina Lücke, Ilona Schelle, Ingo Just, Ralf Gerhard, Andreas Pich
Aineistotyyppi:	Artigo
Kieli:	Inglês
Julkaistu:	Frontiers Media S.A. 2018-12-01
Sarja:	Frontiers in Microbiology
Aiheet:	Rho Ras GTPase large clostridial glucosylating toxins MRM analysis
Linkit:	https://www.frontiersin.org/article/10.3389/fmicb.2018.03078/full
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