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Amarogentin promotes osteoblast differentiation in oestrogen-deficiency-induced osteoporosis rats by modulating the Nrf-2/MAPK/ERK signalling pathway

Introduction The beneficial effect of amarogentin in the management of osteoporosis was determined using in vivo and in vitro methods. Material and methods Experimental osteoporosis was induced in rats via bilateral ovariectomy. Rats were then treated for 5 weeks with amarogentin (50 and 100 mg/kg,...

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Principais autores: Sirui Li, Xianlong Li, Feng He, Rui Jiao, Song Zhang, Zhihua Li
Format: Artigo
Sprog:Inglês
Udgivet: Termedia Publishing House 2019-11-01
Serier:Archives of Medical Science
Fag:
amarogentin
osteoporosis
oestrogen
ovary
osteoblast
inflammation
Online adgang:https://www.archivesofmedicalscience.com/Amarogentin-promotes-osteoblast-differentiation-in-oestrogen-deficiency-induced-osteoporosis,111137,0,2.html
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