Immunological synapse formation between T regulatory cells and cancer-associated fibroblasts promotes tumour development

Abstract Cancer-associated fibroblasts (CAFs) have emerged as a dominant non-hematopoietic cell population in the tumour microenvironment, serving diverse functions in tumour progression. However, the mechanisms via which CAFs influence the anti-tumour immunity remain poorly understood. Here, using...

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Detalhes bibliográficos

Principais autores:	Athina Varveri, Miranta Papadopoulou, Zacharias Papadovasilakis, Ewoud B. Compeer, Aigli-Ioanna Legaki, Anastasios Delis, Vasileia Damaskou, Louis Boon, Sevasti Papadogiorgaki, Martina Samiotaki, Periklis G. Foukas, Aristides G. Eliopoulos, Aikaterini Hatzioannou, Themis Alissafi, Michael L. Dustin, Panayotis Verginis
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Nature Portfolio 2024-06-01
coleção:	Nature Communications
Acesso em linha:	https://doi.org/10.1038/s41467-024-49282-1
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