Physicochemical Stability of Reconstituted Decitabine (Dacogen®) Solutions and Ready-to-Administer Infusion Bags when Stored Refrigerated or Frozen

Profound knowledge about the physicochemical stability is necessary in order to determine the “beyond-use-dates” of ready-to-administer preparations after reconstitution and dilution. This is especially true for unstable azanucleoside drugs like decitabine. The aim of this study was to determine the...

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Hlavní autoři:	Kim Sun Hee, Heeb Rita Marina, Krämer Irene
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	De Gruyter 2017-12-01
Edice:	Pharmaceutical Technology in Hospital Pharmacy
Témata:	decitabine physicochemical stability reconstitution ready-to-administer infusion bag reversed-phase high-performance liquid chromatography (rp-hplc)
On-line přístup:	https://doi.org/10.1515/pthp-2017-0025
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