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The analysis of biodistribution and tumor uptake of [18F]AlF-FAPI-74 in patients with soft tissue sarcoma and gastro-intestinal tumors compared with [18F]FDG in a prospective, exploratory study

Abstract Background The roll-out of FAP (fibroblast-activation-protein) imaging with small-molecule PET tracers marks one of the major breakthroughs in nuclear medicine. The majority of current evidence, however, has been generated by 68Ga-labelled FAPI tracers, a reliance that presents serious econ...

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Main Authors: Emil Novruzov, Frederik L. Giesel, Eduards Mamlins, Tadashi Watabe, Jens Cardinale, Christina Antke, Yuriko Mori, Nils Schupps, Claudio Pinto, Cristian Soza-Ried, Rene Fernandez, Horacio Amaral, Vasko Kramer, Leonardo Badinez
Format: Artigo
Language:Inglês
Published: Springer 2026-03-01
Series:EJNMMI Reports
Subjects:
[18F]AlF-FAPI-74
FAPI-74 PET
18F-labelling
Gastrointestinal tumors
Colorectal carcinoma
Soft tissue tumors
Online Access:https://doi.org/10.1186/s41824-026-00295-7
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