Transformation into acute myeloid leukemia with t(8;21)(q22;q22.1); RUNX1::RUNX1T1 from JAK2-mutated essential thrombocythemia: a case report

Abstract Background Blast transformation is a rare but well-recognized event in Philadelphia-negative myeloproliferative neoplasms associated with a poor prognosis. Secondary acute myeloid leukemias evolving from myeloproliferative neoplasms are characterized by a unique set of cytogenetic and molec...

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Автори:	Chie Asou, Tomoyuki Sakamoto, Kodai Suzuki, Itoko Okuda, Atsushi Osaki, Ryohei Abe, Yoshihiro Ito, Emi Kakegawa, Yoshitaka Miyakawa, Yasuhito Terui, Yuichi Nakamura
Формат:	Artigo
Мова:	Inglês
Опубліковано:	BMC 2024-08-01
Серія:	Journal of Medical Case Reports
Предмети:	Myeloproliferative neoplasms Essential thrombocythemia Secondary acute myeloid leukemia JAK2 V617F t(8;21)(q22;q22.1) RUNX1::RUNX1T1
Онлайн доступ:	https://doi.org/10.1186/s13256-024-04691-0
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