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Polyclonal IgE Induces Mast Cell Survival and Cytokine Production

Background: Ag-dependent activation of IgE-bearing mast cells is a critical first step in immediate hypersensitivity and other allergic responses. Recent studies have revealed Ag-independent effects of monoclonal mouse IgE molecules on mast cell survival and activation. However, no studies have been...

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Main Authors: Jun-ichi Kashiwakura, Yuko Kawakami, Keisuke Yuki, Dirk M Zajonc, Shunji Hasegawa, Yoshiaki Tomimori, Benjamin Caplan, Hirohisa Saito, Masutaka Furue, Hans C Oettgen, Yoshimichi Okayama, Toshiaki Kawakami
Format: Artigo
Language:Inglês
Published: Elsevier 2009-01-01
Series:Allergology International
Subjects:
allergy
antibodies
cell activation
human
mast cells/basophils
Online Access:http://www.sciencedirect.com/science/article/pii/S1323893015307243
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