Development and characterization of anti-CXCR4 chimeric antigen receptor T cells

Acute Myeloid Leukemia (AML) and Acute Lymphoblastic Leukemia (ALL) are aggressive hematologic malignancies characterized by dysregulation of normal hematopoiesis and acquisition of stem-like, self-renewing properties leading to oncogenesis. Current treatments primarily rely on toxic chemotherapies...

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Bibliografiske detaljer

Principais autores:	Gabriel Seir, Quenton Rashawn Bubb, Elena Sotillo, Tanja Gruber, Rebecca M. Richards, Agnieszka Czechowicz
Format:	Artigo
Sprog:	Inglês
Udgivet:	Elsevier 2026-04-01
Serier:	Translational Oncology
Fag:	CAR-T CXCR4 Acute myeloid leukemia Acute lymphoblastic leukemia Hematopoietic stem cell transplantation
Online adgang:	http://www.sciencedirect.com/science/article/pii/S1936523326000483
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