The intracellular portion of GITR enhances NGF-promoted neurite growth through an inverse modulation of Erk and NF-κB signalling

Summary NF-κB transcription factors play a key role in regulating the growth of neural processes in the developing PNS. Although several secreted proteins have been shown to activate NF-κB to inhibit the growth of developing sympathetic neurons, it is unknown how the endogenous level of NF-κB activi...

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Ngā kaituhi matua:	Laura McKelvey, Humberto Gutierrez, Giuseppe Nocentini, Sean J. Crampton, Alun M. Davies, Carlo R. Riccardi, Gerard W. O’keeffe
Hōputu:	Artigo
Reo:	Inglês
I whakaputaina:	The Company of Biologists 2012-08-01
Rangatū:	Biology Open
Ngā marau:	GITR NF-κB NGF Growth Neurite Neuron
Urunga tuihono:	http://bio.biologists.org/content/1/10/1016
Ngā Tūtohu:	Tāpirihia he Tūtohu Kāore He Tūtohu, Me noho koe te mea tuatahi ki te tūtohu i tēnei pūkete!