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Chromatin’s Influence on Pre-Replication Complex Assembly and Function

In all eukaryotes, the initiation of DNA replication requires a stepwise assembly of factors onto the origins of DNA replication. This is pioneered by the Origin Recognition Complex, which recruits Cdc6. Together, they bring Cdt1, which shepherds MCM2-7 to form the OCCM complex. Sequentially, a seco...

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Bibliografiska uppgifter
Huvudupphov: Hina Ahmad, Neha Chetlangia, Supriya G. Prasanth
Materialtyp: Artigo
Språk:Inglês
Utgiven: MDPI AG 2024-02-01
Serie:Biology
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Länkar:https://www.mdpi.com/2079-7737/13/3/152
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