Characterization of ocular adverse events associated with crizotinib: real-world insights from the two global pharmacovigilance databases of FAERS and VigiBase

To evaluate the risk of ocular adverse events (AEs) associated with crizotinib using real-world data from FAERS and VigiBase, and to characterize signal patterns through disproportionality and time-to-onset (TTO) analyses. Reports from FAERS and VigiBase (2011–2025) were analyzed. Disproportionality...

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Hauptverfasser:	Shuai Dong, Zhi-chao Jiang, Li Gao, Rong Zhang, Yan Liu
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	Frontiers Media S.A. 2025-12-01
Schriftenreihe:	Frontiers in Oncology
Schlagworte:	crizotinib ocular adverse events FAERS VigiBase disproportionality analysis
Online-Zugang:	https://www.frontiersin.org/articles/10.3389/fonc.2025.1735200/full
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