OmpA virulence factor, a promising conserved vaccine candidate against Acinetobacter baumannii, could trigger autoreactive immune responses in susceptible population

Abstract The mechanism of epitope mimicry could have implications for the safety of vaccine development. OmpA is one of the most promising antigens of Acinetobacter baumannii. This property convinced us to investigate OmpA’s potential to trigger autoimmune responses. To this end, BLAST searches were...

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Autori principali:	Kobra Ahmadi Zanoos, Othman Jamal Nassrullah, Shaden M. H. Mubarak, Bahman Khalesi, Mohammad Reza Rahbar, Yasmin Zare, Saeed Khalili, Navid Pourzardosht, Moslem Jafarisani, Abolfazl Jahangiri
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	BMC 2025-10-01
Serie:	BMC Immunology
Soggetti:	A. baumannii OmpA Autoantibody Epitope Autoimmune disease Vaccination
Accesso online:	https://doi.org/10.1186/s12865-025-00766-9
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