NLRP3 Inflammasome Activation of Mast Cells by Estrogen via the Nuclear-Initiated Signaling Pathway Contributes to the Development of Endometriosis

Endometriosis is an estrogen-dependent gynecological disease. The pathogenesis of endometriosis remains controversial, although it is generally accepted that the inflammatory immune response plays a crucial role in this process. Mast cells (MCs) are multifunctional innate immune cells that accumulat...

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Główni autorzy:	Xinyue Guo, Xinxin Xu, Tiantian Li, Qin Yu, Jianzhang Wang, Yichen Chen, Shaojie Ding, Libo Zhu, Gen Zou, Xinmei Zhang
Format:	Artigo
Język:	Inglês
Wydane:	Frontiers Media S.A. 2021-09-01
Seria:	Frontiers in Immunology
Hasła przedmiotowe:	endometriosis estrogen mast cells NLRP3 inflammasome interleukin-1β
Dostęp online:	https://www.frontiersin.org/articles/10.3389/fimmu.2021.749979/full
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