The biotherapeutic Clostridium butyricum MIYAIRI 588 strain potentiates enterotropism of Rorγt+Treg and PD-1 blockade efficacy

ABSTRACTImmune checkpoint inhibitors (ICI) have been positioned as a standard of care for patients with advanced non-small-cell lung carcinomas (NSCLC). A pilot clinical trial has reflected optimistic association between supplementation with Clostridium butyricum MIYAIRI 588 (CBM588) and ICI efficac...

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Auteurs principaux:	Thomas Paz Del Socorro, Kentaro Oka, Olivier Boulard, Motomichi Takahashi, Lionel Franz Poulin, Atsushi Hayashi, Mathias Chamaillard
Format:	Artigo
Langue:	Inglês
Publié:	Taylor & Francis Group 2024-12-01
Collection:	Gut Microbes
Sujets:	Immune checkpoint inhibitors interferon gamma interleukin-10 oncomicrobiotic Rorγt+Treg
Accès en ligne:	https://www.tandfonline.com/doi/10.1080/19490976.2024.2315631
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