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Sesamin attenuates atherosclerosis by alleviating vascular endothelial ferroptosis-related injury via m6A-dependent regulation of SREBF1 expression

ObjectiveThis study was designed to elucidate the molecular pathways responsible for anti-atherosclerotic effects of the traditional Chinese medicine formula Yishen Huoxue Huatan, with a focus on its key active component sesamin.MethodsNetwork pharmacology was applied to predict potential targets an...

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Principais autores: Xiaoying Chen, Guanyi Zheng, Kailong Fu, Minglong Yao, Kan Lin
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2026-06-01
coleção:Frontiers in Cell and Developmental Biology
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Acesso em linha:https://www.frontiersin.org/articles/10.3389/fcell.2026.1807359/full
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