M2e nanovaccines supplemented with recombinant hemagglutinin protect chickens against heterologous HPAI H5N1 challenge

Abstract Current poultry vaccines against influenza A viruses target the globular head region of the hemagglutinin (HA1), providing limited protection against antigenically divergent strains. Experimental subunit vaccines based on the conserved ectodomain of the matrix protein 2 (M2e) induce cross-r...

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Váldodahkkit:	Cynthia Calzas, Tamiru N. Alkie, Matthew Suderman, Carissa Embury-Hyatt, Vinay Khatri, Ronan Le Goffic, Yohannes Berhane, Steve Bourgault, Denis Archambault, Christophe Chevalier
Materiálatiipa:	Artigo
Giella:	Inglês
Almmustuhtton:	Nature Portfolio 2024-09-01
Ráidu:	npj Vaccines
Liŋkkat:	https://doi.org/10.1038/s41541-024-00944-7
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