Population Pharmacokinetics of Prophylactic Cefazolin in Cardiac Surgery with Standard and Minimally Invasive Extracorporeal Circulation

The objectives of this study were to develop a population pharmacokinetic model of prophylactically administered cefazolin in patients undergoing cardiac surgery with and without the use of the cardiopulmonary bypass of both existing types—standard (ECC) and minimallyu invasive extracorporeal circul...

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Autors principals:	Petr Šantavý, Martin Šíma, Ondřej Zuščich, Vendula Kubíčková, Danica Michaličková, Ondřej Slanař, Karel Urbánek
Format:	Artigo
Idioma:	Inglês
Publicat:	MDPI AG 2022-11-01
Col·lecció:	Antibiotics
Matèries:	cefazoline nonlinear mixed-effects modeling antibiotic prophylaxis glomerular filtration rate cardiopulmonary bypass
Accés en línia:	https://www.mdpi.com/2079-6382/11/11/1582
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