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Effect of solvent evaporation on the liquid-crystalline order of itraconazole

Abstract Solvent evaporation is widely used for the formation of amorphous active pharmaceutical ingredients. This study investigates the effect of solvent evaporation on the structure of itraconazole – an antifungal drug and a model thermotropic liquid crystal that exhibits nematic and smectic phas...

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Bibliografiske detaljer
Principais autores: Taoufik Lamrani, Luiza Orszulak, Magdalena Tarnacka, Barbara Hachula, Klaudia Nowakowska, Kamil Kaminski, Karolina Jurkiewicz
Format: Artigo
Sprog:Inglês
Udgivet: Nature Portfolio 2025-11-01
Serier:Scientific Reports
Fag:
Online adgang:https://doi.org/10.1038/s41598-025-23979-9
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