A multicentre, patient- and assessor-blinded, non-inferiority, randomised and controlled phase II trial to compare standard and torque teno virus-guided immunosuppression in kidney transplant recipients in the first year after transplantation: TTVguideIT

Abstract Background Immunosuppression after kidney transplantation is mainly guided via plasma tacrolimus trough level, which cannot sufficiently predict allograft rejection and infection. The plasma load of the non-pathogenic and highly prevalent torque teno virus (TTV) is associated with the immun...

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Detalhes bibliográficos

Principais autores:	Frederik Haupenthal, Jette Rahn, Fabrizio Maggi, Fanny Gelas, Philippe Bourgeois, Christian Hugo, Bernd Jilma, Georg A. Böhmig, Harald Herkner, Michael Wolzt, Konstantin Doberer, Matthias Vossen, Daniele Focosi, Hannes Neuwirt, Miriam Banas, Bernhard Banas, Klemens Budde, Ondrej Viklicky, Paolo Malvezzi, Lionel Rostaing, Joris I. Rotmans, Stephan J. L. Bakker, Kathrin Eller, Daniel Cejka, Alberto Molina Pérez, David Rodriguez-Arias, Franz König, Gregor Bond, the TTVguideTX consortium partners
Formato:	Artigo
Idioma:	Inglês
Publicado em:	BMC 2023-03-01
coleção:	Trials
Assuntos:	Kidney transplantation Torque teno virus Immunosuppression Tacrolimus Immunological monitoring Personalised medicine
Acesso em linha:	https://doi.org/10.1186/s13063-023-07216-0
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