The tumor suppressor PTEN and the PDK1 kinase regulate formation of the columnar neural epithelium

Epithelial morphogenesis and stability are essential for normal development and organ homeostasis. The mouse neural plate is a cuboidal epithelium that remodels into a columnar pseudostratified epithelium over the course of 24 hr. Here we show that the transition to a columnar epithelium fails in mu...

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Bibliografiska uppgifter

Huvudupphov:	Joaquim Grego-Bessa, Joshua Bloomekatz, Pau Castel, Tatiana Omelchenko, José Baselga, Kathryn V Anderson
Materialtyp:	Artigo
Språk:	Inglês
Utgiven:	eLife Sciences Publications Ltd 2016-01-01
Serie:	eLife
Ämnen:	epithelial morphogenesis neural tube defect tumor suppressor PI3 kinase
Länkar:	https://elifesciences.org/articles/12034
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