Cartilage regeneration and inflammation modulation in knee osteoarthritis following injection of allogeneic adipose-derived mesenchymal stromal cells: a phase II, triple-blinded, placebo controlled, randomized trial

Abstract Background Intra-articular injection of mesenchymal stromal cells (MSCs) with immunomodulatory features and their paracrine secretion of regenerative factors proposed a noninvasive therapeutic modality for cartilage regeneration in knee osteoarthritis (KOA). Methods Total number of 40 patie...

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Bibliografische Detailangaben

Hauptverfasser:	Bahareh Sadri, Mohammad Hassanzadeh, Abolfazl Bagherifard, Javad Mohammadi, Mehdi Alikhani, Kasra Moeinabadi-Bidgoli, Hoda Madani, Dylana Diaz-Solano, Shahedeh Karimi, Mohammad Mehrazmay, Mehdi Mohammadpour, Massoud Vosough
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	BMC 2023-06-01
Schriftenreihe:	Stem Cell Research & Therapy
Schlagworte:	Mesenchymal stromal cells Knee osteoarthritis Cell-based therapy Regenerative medicine Cartilage regeneration Liquid biomarkers
Online-Zugang:	https://doi.org/10.1186/s13287-023-03359-8
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