Regulatory Role of miR-15a-5p and miR-16-5p in Suppressing Acute Myeloid Leukemia Cell Growth through Target Gene Interaction

Aim: This study aimed to investigate the functional effects of miR-15a-5p and miR-16-5p in AML cell lines (HL-60 and NB4), focusing on their regulation of key target genes.Material and Methods: We initially transfected miR-15a-5p and miR-16-5p mimics into AML cell lines to investigate their regulato...

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Autors principals:	Şeyma Teomete, Murat Kaya, Ilknur Suer, Kıvanç Çefle, Şükrü Palanduz, Şükrü Öztürk
Format:	Artigo
Idioma:	Inglês
Publicat:	Duzce University 2026-04-01
Col·lecció:	Düzce Tıp Fakültesi Dergisi
Matèries:	miR-15a-5p miR-16-5p IGF1R potential target genes AML in vitro study
Accés en línia:	https://dergipark.org.tr/tr/download/article-file/5413303
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