Type I Interferons Ameliorate Zinc Intoxication of Candida glabrata by Macrophages and Promote Fungal Immune Evasion

Summary: Host and fungal pathogens compete for metal ion acquisition during infectious processes, but molecular mechanisms remain largely unknown. Here, we show that type I interferons (IFNs-I) dysregulate zinc homeostasis in macrophages, which employ metallothionein-mediated zinc intoxication of pa...

全面介紹

書目詳細資料

Principais autores:	Michael Riedelberger, Philipp Penninger, Michael Tscherner, Bernhard Hadriga, Carina Brunnhofer, Sabrina Jenull, Anton Stoiber, Christelle Bourgeois, Andriy Petryshyn, Walter Glaser, Andreas Limbeck, Michael A. Lynes, Gernot Schabbauer, Guenter Weiss, Karl Kuchler
格式:	Artigo
語言:	Inglês
出版:	Elsevier 2020-05-01
叢編:	iScience
主題:	Immunology Immune Respons Immune Response
在線閱讀:	http://www.sciencedirect.com/science/article/pii/S2589004220303060
標簽:	添加標簽 沒有標簽, 成為第一個標記此記錄!