Uracil Accumulation and Mutagenesis Dominated by Cytosine Deamination in CpG Dinucleotides in Mice Lacking UNG and SMUG1
Abstract Both a DNA lesion and an intermediate for antibody maturation, uracil is primarily processed by base excision repair (BER), either initiated by uracil-DNA glycosylase (UNG) or by single-strand selective monofunctional uracil DNA glycosylase (SMUG1). The relative in vivo contributions of eac...
Kaydedildi:
| Asıl Yazarlar: | , , , , , , , , , , , , , , , |
|---|---|
| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
Nature Portfolio
2017-08-01
|
| Seri Bilgileri: | Scientific Reports |
| Online Erişim: | https://doi.org/10.1038/s41598-017-07314-5 |
| Etiketler: |
Etiket eklenmemiş, İlk siz ekleyin!
|