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Urine Stasis Predisposes to Urinary Tract Infection by an Opportunistic Uropathogen in the Megabladder (Mgb) Mouse.

Urinary stasis is a risk factor for recurrent urinary tract infection (UTI). Homozygous mutant Megabladder (Mgb-/-) mice exhibit incomplete bladder emptying as a consequence of congenital detrusor aplasia. We hypothesize that this predisposes Mgb-/- mice to spontaneous and experimental UTI.Mgb-/-, M...

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Bibliografiset tiedot
Päätekijät: Brian Becknell, Ahmad Z Mohamed, Birong Li, Michael E Wilhide, Susan E Ingraham
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Public Library of Science (PLoS) 2015-01-01
Sarja:PLoS ONE
Linkit:http://europepmc.org/articles/PMC4581623?pdf=render
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