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Age-dependent molecular variations in osteosarcoma: implications for precision oncology across pediatric, adolescent, and adult patients

BackgroundOsteosarcoma is a leading subtype of bone tumor affecting adolescents and adults. Comparative molecular characterization among different age groups, especially in pediatric, adolescents and adults, is scarce.MethodsWe collected samples from 194 osteosarcoma patients, encompassing pediatric...

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Principais autores: Changye Zou, Renxuan Huang, Tiao Lin, Yaxian Wang, Jian Tu, Liwen Zhang, Bo Wang, Jintao Huang, Zhiqiang Zhao, Xianbiao Xie, Gang Huang, Kai Wang, Junqiang Yin, Jingnan Shen
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2024-05-01
Serier:Frontiers in Oncology
Fag:
osteosarcoma
pediatrics
adolescents
adults
genomic alteration
next generation sequencing
Online adgang:https://www.frontiersin.org/articles/10.3389/fonc.2024.1382276/full
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