Exploring the key molecular mechanisms and immune microenvironment of oxidative stress-related pathways in pancreatic neuroendocrine tumor combining scRNA-seq and bulk RNA

Abstract Background Pancreatic neuroendocrine tumor (pNET) is a heterogeneous tumor originating from pancreatic endocrine cells. Emerging evidence suggests that oxidative stress plays a crucial role in pNET pathogenesis, yet the precise molecular mechanisms and their interplay with the tumor microen...

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Bibliografiska uppgifter

Huvudupphov:	Zhong Cai, Jiangtao Li, Ting Li, Qiuxia Peng
Materialtyp:	Artigo
Språk:	Inglês
Utgiven:	Springer 2026-01-01
Serie:	Discover Oncology
Ämnen:	Pancreatic neuroendocrine tumor Oxidative stress Single-cell RNA sequencing Immune microenvironment CeRNA network
Länkar:	https://doi.org/10.1007/s12672-026-04515-1
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