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Optical microelastography via a 2D boundary condition-free nonlinear inversion approach

The mechanical phenotype of a cell, including its viscoelastic properties, is recognized as a label-free biomarker for diagnosing cellular states. Optical microelastography (OME) assesses intracellular mechanical heterogeneity by mapping the shear modulus distribution within cells using time-harmoni...

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Autori principali: Sajad Ghazavi, Hari S. Nair, Guillaume Flé, Boris Chayer, Ruchi Goswami, Salvatore Girardo, Jochen Guck, Guy Cloutier, Elijah E. W. Van Houten
Natura: Artigo
Lingua:Inglês
Pubblicazione: Frontiers Media S.A. 2026-01-01
Serie:Frontiers in Physics
Soggetti:
cell mechanics
inverse problem
loss modulus
optical microelastography
optical microscopy
storage modulus
Accesso online:https://www.frontiersin.org/articles/10.3389/fphy.2025.1734499/full
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