Risk factors for voriconazole-associated hepatotoxicity in patients with liver dysfunction: a retrospective nested case–control study

IntroductionVoriconazole is widely used to prevent and treat invasive aspergillosis. However, its use is restricted by adverse effects, including acute liver injury (ALI). Patients with hepatic insufficiency are often more susceptible to voriconazole-induced liver injury than those with normal hepat...

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Bibliografische Detailangaben

Hauptverfasser:	Jing Ren, Xinfeng Cai, Wei Ge, Jinlin Guo, Shan Wang, Qinhui Wang, Linna Liu, Le Yang, Qi Yang
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	Frontiers Media S.A. 2025-08-01
Schriftenreihe:	Frontiers in Pharmacology
Schlagworte:	voriconazole hepatotoxicity acute liver injury therapeutic drug monitoring trough concentration
Online-Zugang:	https://www.frontiersin.org/articles/10.3389/fphar.2025.1625003/full
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