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Cell-penetrating peptide-functionalized biomimetic nanovesicles for efficient cataract treatment via enhanced corneal penetration and lens-mitochondria dual targeting

Cataract is the leading cause of blindness worldwide. While the oxidative stress homeostasis unbalance of the lens is a key pathological mechanism underlying cataract formation. Due to the lens being deeply embedded behind multiple biological barriers, there is no effective drug treatment for catara...

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Principais autores: Renjie Zhang, Wei Li, Jiahao Wang, Yijin Li, Jiang Chen, Wenxin Hong, Huiying Huang, Quankui Lin
Formato: Artigo
Idioma:Inglês
Publicado em: KeAi Communications Co., Ltd. 2026-03-01
coleção:Bioactive Materials
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Acesso em linha:http://www.sciencedirect.com/science/article/pii/S2452199X25005377
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