A dual-drug strategy to enhance the function of cryopreserved ovaries by promoting revascularization and inhibiting follicle over-activation

Abstract Background Ovarian tissue cryopreservation and transplantation (OTCT) is a promising approach for fertility preservation. However, significant follicle loss after transplantation challenges long-term reproductive recovery. Although primordial follicle loss and ischemic damage are known cont...

Szczegółowa specyfikacja

Opis bibliograficzny

Główni autorzy:	Lingyu Li, Jian Yang, Longzhong Jia, Jing Liang, Kaixin Cheng, Xuebing Yang, Lu Mu, Ge Wang, Kaiying Geng, Qiuxian Hu, Xueqiang Xu, Zhen Li, Guoliang Xia, Ting Guo, Jiawei Zhang, Yan Zhang, Hua Zhang
Format:	Artigo
Język:	Inglês
Wydane:	BMC 2025-07-01
Seria:	Reproductive Biology and Endocrinology
Hasła przedmiotowe:	Ovarian cryopreservation 3D high resolution imaging Tip cell Long-term fertility preservation Primordial follicle activation
Dostęp online:	https://doi.org/10.1186/s12958-025-01422-y
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