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A chemically induced attenuated strain of Candida albicans generates robust protective immune responses and prevents systemic candidiasis development

Despite current antifungal therapy, invasive candidiasis causes >40% mortality in immunocompromised individuals. Therefore, developing an antifungal vaccine is a priority. Here, we could for the first time successfully attenuate the virulence of Candida albicans by treating it with a fungistatic...

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Principais autores: Swagata Bose, Satya Ranjan Sahu, Abinash Dutta, Narottam Acharya
Formato: Artigo
Idioma:Inglês
Publicado em: eLife Sciences Publications Ltd 2024-05-01
coleção:eLife
Assuntos:
Acesso em linha:https://elifesciences.org/articles/93760
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