Multi-omics-based construction of a palmitoylation-driven prognostic model reveals tumor immune phenotypes in osteosarcoma

Abstract Background Osteosarcoma (OS), the leading primary malignancy of bone in adolescents, is known for its aggressive metastatic behavior and poor responsiveness to conventional therapies. As a lipid-mediated post-translational modification, protein palmitoylation has gained attention for its pi...

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Detalhes bibliográficos

Principais autores:	Jingyu Chen, Feihu Chen, Haiping Zhang, Yuanlong Hu, Xingyu Zhou, Xijia Weng, Guofeng Bao, Xiaomin Ding
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Springer 2025-08-01
coleção:	Discover Oncology
Assuntos:	Osteosarcoma Palmitoylation Prognostic signature Single-cell RNA sequencing Tumor microenvironment
Acesso em linha:	https://doi.org/10.1007/s12672-025-03364-8
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