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Indomethacin promotes survival of new neurons in the adult murine hippocampus accompanied by anti-inflammatory effects following MPTP-induced dopamine depletion

Abstract Background Parkinson’s disease (PD) is characterized by dopaminergic cell loss and inflammation in the substantia nigra (SN) leading to motor deficits but also to hippocampus-associated non-motor symptoms such as spatial learning and memory deficits. The cognitive decline is correlated with...

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Principais autores: Elisabeth G. Hain, Maria Sparenberg, Justyna Rasińska, Charlotte Klein, Levent Akyüz, Barbara Steiner
Formato: Artigo
Idioma:Inglês
Publicado em: BMC 2018-05-01
coleção:Journal of Neuroinflammation
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Acesso em linha:http://link.springer.com/article/10.1186/s12974-018-1179-4
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