Protective effects of dioscin against Parkinson's disease via regulating bile acid metabolism through remodeling gut microbiome/GLP-1 signaling

It is necessary to explore potent therapeutic agents via regulating gut microbiota and metabolism to combat Parkinson's disease (PD). Dioscin, a bioactive steroidal saponin, shows various activities. However, its effects and mechanisms against PD are limited. In this study, dioscin dramatically alle...

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Bibliografische gegevens

Hoofdauteurs:	Zhang Mao, Haochen Hui, Xuerong Zhao, Lina Xu, Yan Qi, Lianhong Yin, Liping Qu, Lan Han, Jinyong Peng
Formaat:	Artigo
Taal:	Inglês
Gepubliceerd in:	Elsevier 2023-10-01
Reeks:	Journal of Pharmaceutical Analysis
Onderwerpen:	Parkinson's disease Dioscin Gut microbiota Bile acid metabolism GLP-1
Online toegang:	http://www.sciencedirect.com/science/article/pii/S2095177923001193
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